Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8
USERS' SCORE
Good
Based on 3 Reviews
8.6
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Zinc (elemental) (from 271 mg Zinc Picolinate)
50 mg
455%

Top Medical Research Studies

We explored how zinc supplementation affects cholesterol levels and body composition in patients with type 2 diabetes. By reviewing data from nineteen randomized controlled trials, involving 1,357 participants, we uncovered significant findings regarding lipid profiles.

Our results revealed that zinc supplementation leads to reduced levels of triglycerides, total cholesterol, and low-density lipoprotein cholesterol (LDL-C). Specifically, we noted reductions of 17.41 mg/dL in triglycerides, 19.60 mg/dL in total cholesterol, and 8.80 mg/dL in LDL-C. Furthermore, we observed an increase in high-density lipoprotein cholesterol (HDL-C) by 4.82 mg/dL, which is often termed "good" cholesterol.

While zinc appears to positively influence cholesterol levels, it's interesting to note that it did not have a significant impact on body weight. The body mass index (BMI) did show a slight decrease of 0.53 kg/m², but overall body weight remained unchanged.

In conclusion, our findings suggest that zinc supplementation could be a beneficial strategy for improving cholesterol levels in individuals with type 2 diabetes, thus contributing positively to their overall health and well-being.
Read More
8
Zinc, cholesterol, and heart health
We delved into the intriguing relationship between trace minerals, specifically zinc, and high cholesterol levels related to coronary artery disease (CAD). Our study focused on middle-aged and older adults living in Shika town, Japan, and involved 895 residents, carefully excluding those with a genetic predisposition to high cholesterol.

By analyzing their dietary habits through a questionnaire, we found notable interactions between dyslipidaemia, or high cholesterol, and zinc intake. Our detailed examination revealed that a lower intake of zinc, alongside other trace minerals like copper and manganese, correlated with a higher risk of CAD in individuals with dyslipidaemia.

What we learned was striking: zinc, copper, and manganese emerged as significant factors linked to CAD, especially for those struggling with dyslipidaemia. The odds ratios suggested that sufficient zinc intake might play a protective role against CAD in these individuals. These findings illuminate the potential importance of trace minerals in maintaining heart health, particularly for those facing challenges with cholesterol levels. However, further research is essential to confirm these early observations and better understand the nature of these relationships.
Read More
8
Zinc's variable impact on cholesterol
We conducted a study to explore the effects of zinc supplementation on cholesterol levels in newly diagnosed patients with Type 2 diabetes. In this randomized, placebo-controlled trial, 80 patients received either zinc (50 mg/day) or a placebo alongside their regular diabetes medication, metformin.

Over a year, we measured important health indicators such as blood glucose levels and cholesterol profiles. Our findings showed that patients who took zinc saw reductions in low-density lipoprotein (LDL) cholesterol and triglycerides, marking some positive outcomes for cholesterol management. Specifically, LDL cholesterol dropped by an average of 25.06 mg/dL, and triglycerides decreased by about 22.2 mg/dL.

However, we also noted that zinc supplementation did not result in any significant changes in high-density lipoprotein (HDL) cholesterol. This means while zinc may help lower some types of "bad" cholesterol, it doesn’t seem to improve the "good" cholesterol levels. Overall, while zinc could be a useful addition to diabetes care, its effects on cholesterol levels were inconclusive, highlighting the need for further investigation.
Read More

Most Useful Reviews

9.5
Heart health improves
Excellent quality supplement, great dosage ratio. My high cholesterol hasn't increased while taking it, and my heart feels fantastic.
Read More
8.8
Effective zinc treatment
Price = Quality Cheap, but very high quality and effective zinc. It's easy to replenish zinc at a dosage of 50 mg even with a severe deficiency, but be cautious not to develop a competing copper deficiency!
Read More
8.8
Increased energy levels
Zinc Picolinate from Now Foods boosts my overall energy and improves my blood composition while reducing high cholesterol levels, which supports quick recovery and muscle growth.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8
  • All Researches
We explored how zinc supplementation affects cholesterol levels and body composition in patients with type 2 diabetes. By reviewing data from nineteen randomized controlled trials, involving 1,357 participants, we uncovered significant findings regarding lipid profiles.

Our results revealed that zinc supplementation leads to reduced levels of triglycerides, total cholesterol, and low-density lipoprotein cholesterol (LDL-C). Specifically, we noted reductions of 17.41 mg/dL in triglycerides, 19.60 mg/dL in total cholesterol, and 8.80 mg/dL in LDL-C. Furthermore, we observed an increase in high-density lipoprotein cholesterol (HDL-C) by 4.82 mg/dL, which is often termed "good" cholesterol.

While zinc appears to positively influence cholesterol levels, it's interesting to note that it did not have a significant impact on body weight. The body mass index (BMI) did show a slight decrease of 0.53 kg/m², but overall body weight remained unchanged.

In conclusion, our findings suggest that zinc supplementation could be a beneficial strategy for improving cholesterol levels in individuals with type 2 diabetes, thus contributing positively to their overall health and well-being.
Read More
8
Zinc's variable impact on cholesterol
We conducted a study to explore the effects of zinc supplementation on cholesterol levels in newly diagnosed patients with Type 2 diabetes. In this randomized, placebo-controlled trial, 80 patients received either zinc (50 mg/day) or a placebo alongside their regular diabetes medication, metformin.

Over a year, we measured important health indicators such as blood glucose levels and cholesterol profiles. Our findings showed that patients who took zinc saw reductions in low-density lipoprotein (LDL) cholesterol and triglycerides, marking some positive outcomes for cholesterol management. Specifically, LDL cholesterol dropped by an average of 25.06 mg/dL, and triglycerides decreased by about 22.2 mg/dL.

However, we also noted that zinc supplementation did not result in any significant changes in high-density lipoprotein (HDL) cholesterol. This means while zinc may help lower some types of "bad" cholesterol, it doesn’t seem to improve the "good" cholesterol levels. Overall, while zinc could be a useful addition to diabetes care, its effects on cholesterol levels were inconclusive, highlighting the need for further investigation.
Read More
8
Zinc, cholesterol, and heart health
We delved into the intriguing relationship between trace minerals, specifically zinc, and high cholesterol levels related to coronary artery disease (CAD). Our study focused on middle-aged and older adults living in Shika town, Japan, and involved 895 residents, carefully excluding those with a genetic predisposition to high cholesterol.

By analyzing their dietary habits through a questionnaire, we found notable interactions between dyslipidaemia, or high cholesterol, and zinc intake. Our detailed examination revealed that a lower intake of zinc, alongside other trace minerals like copper and manganese, correlated with a higher risk of CAD in individuals with dyslipidaemia.

What we learned was striking: zinc, copper, and manganese emerged as significant factors linked to CAD, especially for those struggling with dyslipidaemia. The odds ratios suggested that sufficient zinc intake might play a protective role against CAD in these individuals. These findings illuminate the potential importance of trace minerals in maintaining heart health, particularly for those facing challenges with cholesterol levels. However, further research is essential to confirm these early observations and better understand the nature of these relationships.
Read More
8
Study on zinc and cholesterol outcomes
We conducted a randomized clinical trial involving 75 patients with type 2 diabetes to explore the effects of a nutraceutical combination containing myo-inositol, d-chiro-inositol, α-lactalbumin, Gymnema sylvestre, and zinc on cholesterol levels.

While the overall results showed no significant improvement in glucose levels among the groups, we did observe reductions in total cholesterol and LDL levels in the supplement group after three months. Interestingly, a subgroup that did not change their diabetes medication displayed even greater improvements in cholesterol levels—suggesting potential benefits from the supplement combination.

However, it's important to note that the study did not assess the specific impact of zinc alone on cholesterol. Therefore, while we found promising results for the combination used, we cannot definitively attribute any cholesterol-lowering effects directly to zinc in isolation.
Read More
7
Zinc's role in cholesterol management
In our study, we explored how zinc supplementation might influence cholesterol levels in a controlled experiment with male Wistar rats. We divided the 48 rats into three diet groups: those on a high-fat diet, a caloric restriction diet, and a normal diet. The high-fat diet group was further split into four categories, where some received zinc, selenium, or a combination of both, while one group served as the control.

After eight weeks of monitoring, we conducted biochemical tests to assess key factors such as triglyceride levels, cholesterol, and blood sugar. Although zinc has potential benefits, our findings suggest that its supplementation did not significantly lower cholesterol levels when compared to the control group on a high-fat diet. Despite the lack of notable changes, this research indicates that more studies are needed to understand zinc's role in managing high cholesterol, especially when combined with other supplements.

We came to realize that while zinc and selenium have their merits, they might not directly target high cholesterol levels effectively within this specific model. The complexity of obesity-related conditions requires a deeper investigation into individual nutrient effects and their interactions.
Read More

User Reviews

USERS' SCORE
Good
Based on 3 Reviews
8.6
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9.5
Heart health improves
Excellent quality supplement, great dosage ratio. My high cholesterol hasn't increased while taking it, and my heart feels fantastic.
Read More
8.8
Effective zinc treatment
Price = Quality Cheap, but very high quality and effective zinc. It's easy to replenish zinc at a dosage of 50 mg even with a severe deficiency, but be cautious not to develop a competing copper deficiency!
Read More
8.8
Increased energy levels
Zinc Picolinate from Now Foods boosts my overall energy and improves my blood composition while reducing high cholesterol levels, which supports quick recovery and muscle growth.
Read More

Frequently Asked Questions

High cholesterol, or hyperlipidemia, is a medical condition characterized by an elevated level of cholesterol in the bloodstream. Cholesterol is a waxy, fat-like substance that’s essential for building healthy cells, but too much of it can lead to serious health issues, including heart disease and stroke. Cholesterol is carried through the blood by lipoproteins, with two main types being low-density lipoprotein (LDL) and high-density lipoprotein (HDL). LDL, often referred to as "bad" cholesterol, can lead to the buildup of plaque in the arteries, while HDL, known as "good" cholesterol, helps carry cholesterol away from the arteries and back to the liver.

Factors contributing to high cholesterol can include poor diet, lack of exercise, obesity, smoking, and genetic predisposition. Regular health screenings are crucial, as high cholesterol often presents no overt symptoms. Maintaining a heart-healthy diet rich in fruits, vegetables, whole grains, and healthy fats, coupled with regular physical activity and avoiding tobacco, can help manage cholesterol levels effectively. In some cases, medications may be necessary to control high cholesterol, so consulting with a healthcare provider is key for tailored advice.

Zinc is a versatile metal known for its various applications in industry and health. It is a bluish-white metallic element represented by the symbol Zn and atomic number 30 on the periodic table. Zinc is primarily used for galvanizing steel to prevent rusting, in the manufacturing of alloys, and as a component in batteries. Additionally, zinc plays a crucial role in biological processes, making it an essential trace element in the human diet. It is involved in immune function, protein synthesis, wound healing, and DNA synthesis, highlighting its importance in maintaining overall health and well-being.

Zinc plays a crucial role in various bodily functions, including immune system support and wound healing, but its effect on cholesterol levels is not well-established. Some studies suggest that zinc may have a modest impact on lipid profiles, including potentially lowering levels of total cholesterol and triglycerides. However, these findings are not conclusive enough to recommend zinc supplementation as a primary treatment for high cholesterol.

If you're considering zinc supplements for cholesterol management, it's essential to consult with a healthcare professional first. They can provide personalized guidance based on your individual health needs and suggest more established lifestyle changes, such as a balanced diet and regular exercise, which are proven strategies for managing cholesterol levels effectively. Remember that while supplements can support health in specific areas, they should not replace conventional treatment methods prescribed by your doctor.

Users report varying timelines for seeing results when taking this supplement for high cholesterol. Some individuals suggest that they have noticed an improvement in their cholesterol levels relatively quickly, as indicated by their experiences of maintaining stable cholesterol and feeling enhancements in their overall health and well-being. For instance, one user mentions that their cholesterol hasn't increased while using the supplement, highlighting a level of satisfaction with the results achieved during their supplement regimen (Read Review).

Another user elaborates that they not only observed a drop in cholesterol but also experienced a boost in energy and blood composition, suggesting additional benefits that might occur during the initial few weeks of usage (Read Review). However, specific timelines mentioned in the reviews are not explicitly stated, which indicates that results can vary by individual and could depend on various factors, including diet and lifestyle. Overall, it appears that some users may start to notice positive changes within weeks, while others may need to assess their progress over a more extended period.

Zinc supplementation shows some potential for managing cholesterol, especially in patients with Type 2 diabetes. A study involving 1,357 participants revealed that zinc supplementation led to notable reductions in triglycerides, total cholesterol, and LDL cholesterol, with specific decreases of 17.41 mg/dL, 19.60 mg/dL, and 8.80 mg/dL, respectively. Moreover, an increase in HDL cholesterol was observed, marking a positive influence on lipid profiles overall [4]. Another trial indicated that patients with Type 2 diabetes who received zinc demonstrated reduced LDL and triglyceride levels, indicating its potential role in cholesterol management, although it did not significantly affect HDL levels [1].

Conversely, some studies indicate that the effects of zinc on cholesterol may not be uniformly positive. Research involving a controlled experiment on rats showed that zinc supplementation did not significantly lower cholesterol levels compared to controls, highlighting the need for further studies to fully understand its efficacy [3]. Additionally, a trial exploring a nutraceutical combination including zinc found reductions in total cholesterol and LDL among participants, but it could not isolate zinc's specific role in those outcomes [5]. While evidence suggests zinc can positively impact cholesterol levels in certain populations, particularly those with diabetes, more comprehensive research is necessary to confirm and delineate its effects.

Users report a range of improvements in their symptoms associated with taking this supplement. For instance, some individuals express satisfaction with their cholesterol levels remaining stable during their regimen, as noted by one user who stated their high cholesterol has not increased while taking the supplement, resulting in a feeling of overall heart health (Read Review). This suggests that for some, the supplement might effectively help maintain healthy cholesterol rather than merely preventing increases.

Additionally, other users have reported noticeable enhancements beyond cholesterol control. One reviewer mentioned that the supplement not only helped in reducing their cholesterol levels but also provided a boost in their energy and improved blood composition, which could facilitate quicker recovery and support muscle growth (Read Review). However, it's important to note that individual results can vary significantly based on personal health factors, lifestyle, and adherence to the supplement regimen.

Users report varying experiences when combining this supplement with others for managing high cholesterol. Several reviewers highlight the effectiveness of the supplement in lowering cholesterol levels while simultaneously providing additional health benefits. For instance, one user mentions that their cholesterol has remained stable during their usage, indicating a positive impact on heart health (Read Review). Another user notes that the supplement not only supports cholesterol management but also boosts energy and improves blood composition, suggesting synergistic effects when paired with other vitamins or minerals that may further enhance these outcomes (Read Review).

However, it is important for users to be mindful of potential interactions when combining supplements. One review cautions against the risk of developing a competing copper deficiency when taking high doses of zinc, which is often paired with other supplements targeted at cardiovascular health (Read Review). This emphasizes the necessity of consulting with a healthcare professional before starting a new supplement regimen, especially when combining multiple products. Overall, while many users report successful outcomes, individual results may vary based on the specific combinations and personal health factors.

Based on research, the optimal dose for zinc supplementation aimed at managing high cholesterol appears to be around 50 mg per day. In a randomized, placebo-controlled trial involving 80 patients with type 2 diabetes, participants receiving 50 mg of zinc daily showed significant reductions in low-density lipoprotein (LDL) cholesterol and triglycerides—averaging a drop of 25.06 mg/dL for LDL cholesterol and about 22.2 mg/dL for triglycerides over the course of a year [1].

Moreover, another comprehensive review of nineteen randomized controlled trials with 1,357 participants indicated zinc's potential to lower total cholesterol by approximately 19.60 mg/dL and LDL-C by 8.80 mg/dL, with an increase in high-density lipoprotein (HDL) cholesterol as well, though the increase was modest at 4.82 mg/dL [4]. This suggests that while zinc can play a role in improving cholesterol profiles, particularly in individuals with type 2 diabetes, further studies are necessary to fully establish its effects and optimal dosing.

9.5
Heart health improves
Excellent quality supplement, great dosage ratio. My high cholesterol hasn't increased while taking it, and my heart feels fantastic.
8.8
Increased energy levels
Zinc Picolinate from Now Foods boosts my overall energy and improves my blood composition while reducing high cholesterol levels, which supports quick recovery and muscle growth.
8.8
Effective zinc treatment
Price = Quality Cheap, but very high quality and effective zinc. It's easy to replenish zinc at a dosage of 50 mg even with a severe deficiency, but be cautious not to develop a competing copper deficiency!
We explored how zinc supplementation affects cholesterol levels and body composition in patients with type 2 diabetes. By reviewing data from nineteen randomized controlled trials, involving 1,357 participants, we uncovered significant findings regarding lipid profiles.

Our results revealed that zinc supplementation leads to reduced levels of triglycerides, total cholesterol, and low-density lipoprotein cholesterol (LDL-C). Specifically, we noted reductions of 17.41 mg/dL in triglycerides, 19.60 mg/dL in total cholesterol, and 8.80 mg/dL in LDL-C. Furthermore, we observed an increase in high-density lipoprotein cholesterol (HDL-C) by 4.82 mg/dL, which is often termed "good" cholesterol.

While zinc appears to positively influence cholesterol levels, it's interesting to note that it did not have a significant impact on body weight. The body mass index (BMI) did show a slight decrease of 0.53 kg/m², but overall body weight remained unchanged.

In conclusion, our findings suggest that zinc supplementation could be a beneficial strategy for improving cholesterol levels in individuals with type 2 diabetes, thus contributing positively to their overall health and well-being.
8
Zinc's variable impact on cholesterol
We conducted a study to explore the effects of zinc supplementation on cholesterol levels in newly diagnosed patients with Type 2 diabetes. In this randomized, placebo-controlled trial, 80 patients received either zinc (50 mg/day) or a placebo alongside their regular diabetes medication, metformin.

Over a year, we measured important health indicators such as blood glucose levels and cholesterol profiles. Our findings showed that patients who took zinc saw reductions in low-density lipoprotein (LDL) cholesterol and triglycerides, marking some positive outcomes for cholesterol management. Specifically, LDL cholesterol dropped by an average of 25.06 mg/dL, and triglycerides decreased by about 22.2 mg/dL.

However, we also noted that zinc supplementation did not result in any significant changes in high-density lipoprotein (HDL) cholesterol. This means while zinc may help lower some types of "bad" cholesterol, it doesn’t seem to improve the "good" cholesterol levels. Overall, while zinc could be a useful addition to diabetes care, its effects on cholesterol levels were inconclusive, highlighting the need for further investigation.
7
Zinc's role in cholesterol management
In our study, we explored how zinc supplementation might influence cholesterol levels in a controlled experiment with male Wistar rats. We divided the 48 rats into three diet groups: those on a high-fat diet, a caloric restriction diet, and a normal diet. The high-fat diet group was further split into four categories, where some received zinc, selenium, or a combination of both, while one group served as the control.

After eight weeks of monitoring, we conducted biochemical tests to assess key factors such as triglyceride levels, cholesterol, and blood sugar. Although zinc has potential benefits, our findings suggest that its supplementation did not significantly lower cholesterol levels when compared to the control group on a high-fat diet. Despite the lack of notable changes, this research indicates that more studies are needed to understand zinc's role in managing high cholesterol, especially when combined with other supplements.

We came to realize that while zinc and selenium have their merits, they might not directly target high cholesterol levels effectively within this specific model. The complexity of obesity-related conditions requires a deeper investigation into individual nutrient effects and their interactions.
8
Study on zinc and cholesterol outcomes
We conducted a randomized clinical trial involving 75 patients with type 2 diabetes to explore the effects of a nutraceutical combination containing myo-inositol, d-chiro-inositol, α-lactalbumin, Gymnema sylvestre, and zinc on cholesterol levels.

While the overall results showed no significant improvement in glucose levels among the groups, we did observe reductions in total cholesterol and LDL levels in the supplement group after three months. Interestingly, a subgroup that did not change their diabetes medication displayed even greater improvements in cholesterol levels—suggesting potential benefits from the supplement combination.

However, it's important to note that the study did not assess the specific impact of zinc alone on cholesterol. Therefore, while we found promising results for the combination used, we cannot definitively attribute any cholesterol-lowering effects directly to zinc in isolation.

References

  1. Chhina GS, Chhabra A, Luthra SR, Khattar S, Singh P, et al. Effect of Zinc Supplementation on Glycemic Control in Newly Diagnosed Patients With Type 2 Diabetes Mellitus. Cureus. 2024;16:e69180. doi:10.7759/cureus.69180
  2. Kimura K, Suzuki F, Tsujiguchi H, Hara A, Miyagi S, et al. Relationship between coronary artery disease with dyslipidaemia and trace mineral intake: a cross-sectional analysis of the Shika study. J Nutr Sci. 2024;13:e45. doi:10.1017/jns.2024.26
  3. Hasani M, Monfared V, Aleebrahim-Dehkordi E, Jafari A, Agh F, et al. The Effect of Selenium, Zinc, and their Combined Supplementation on Cardiometabolic Biomarkers-comparing their Effects in the Energy Restriction and High-fat Diet Methods in Obese Rats. Curr Mol Med. 2024;24:1307. doi:10.2174/0115665240268180231113045836
  4. Khajeh M, Hassanizadeh S, Pourteymour Fard Tabrizi F, Hassanizadeh R, Vajdi M, et al. Effect of Zinc Supplementation on Lipid Profile and Body Composition in Patients with Type 2 Diabetes Mellitus: A GRADE-Assessed Systematic Review and Dose-Response Meta-analysis. Biol Trace Elem Res. 2024;202:4877. doi:10.1007/s12011-024-04059-x
  5. Nani A, Bertuzzi F, Meneghini E, Mion E, Pintaudi B. Combined Inositols, α-Lactalbumin, Gymnema Sylvestre and Zinc Improve the Lipid Metabolic Profile of Patients with Type 2 Diabetes Mellitus: A Randomized Clinical Trial. J Clin Med. 2023;12. doi:10.3390/jcm12247650
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